![]() Multivariate analyses showed a strong familial aggregation of myopia among siblings (lambda(R) ranging from 2.09 to 3.86) and parent-offspring pairs (lambda(R) from 1.82 to 3.81) adjusted for age, sex, height, and education. Familial aggregation of myopia was evaluated with odds ratios and recurrence risk ratios (lambda(R)) using a multiple logistic regression with generalised estimating equations (GEE), adjusted for age, sex, height, and education. Three definitions of myopia, as the spherical equivalent of -0.5, -1, and -2 diopters or less, were used. Refraction data obtained from 3321 participants aged 16 years and over are presented. ![]() These were from 1259 nuclear families with the average size of 3.6. Of 6497 citizens of Tehran sampled from 160 clusters using stratified random cluster sampling, 4565 (70.3%) participated in the study and were referred to a clinic for an extensive eye examination and interview. To determine the potential influence of genetic factors on the prevalence of myopia in Tehran. ![]()
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